BindingDB PrimarySearch_ki

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BDBM414007 US10421760, Comparative Example 2

SMILES: C\C=C\C(=O)NC1CCC=C(C1)c1ncnc2[nH]cc(-c3ccccc3)c12

InChI Key: InChIKey=GFBWBTIMWXVESY-UHFFFAOYSA-N

Data: 3 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 414007
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Tyrosine-protein kinase JAK1 (Human)	BDBM414007 (US10421760, Comparative Example 2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Human)	BDBM414007 (US10421760, Comparative Example 2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Human)	BDBM414007 (US10421760, Comparative Example 2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair