BDBM4293 (2E)-3-(3,4-dihydroxyphenyl)-2-[(3,4-dihydroxyphenyl)carbonyl]prop-2-enenitrile::3,4-Dihydroxy-a-(3,4-dihydroxybenzoyl)-cis-cinnamonitrile 2-Cyano-3 ,4 -dihydroxyacetophenone::Tyrphostin deriv. 24::cid_5328760

SMILES: Oc1ccc(\C=C(/C#N)C(=O)c2ccc(O)c(O)c2)cc1O

InChI Key: InChIKey=CANOJKGQDCJDOX-UHFFFAOYSA-N

Data: 15 IC50  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 4293   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alkaline phosphatase, germ cell type (Human)	BDBM4293 ((2E)-3-(3,4-dihydroxyphenyl)-2-[(3,4-dihydroxyphen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM4293 ((2E)-3-(3,4-dihydroxyphenyl)-2-[(3,4-dihydroxyphen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM4293 ((2E)-3-(3,4-dihydroxyphenyl)-2-[(3,4-dihydroxyphen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Insulin-like growth factor 1 receptor (Human)	BDBM4293 ((2E)-3-(3,4-dihydroxyphenyl)-2-[(3,4-dihydroxyphen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM4293 ((2E)-3-(3,4-dihydroxyphenyl)-2-[(3,4-dihydroxyphen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
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DNA-(apurinic or apyrimidinic site) endonuclease (Human)	BDBM4293 ((2E)-3-(3,4-dihydroxyphenyl)-2-[(3,4-dihydroxyphen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
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PC4 and SFRS1-interacting protein (Human)	BDBM4293 ((2E)-3-(3,4-dihydroxyphenyl)-2-[(3,4-dihydroxyphen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	79.5	n/a	n/a	n/a	n/a	n/a	n/a
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PC4 and SFRS1-interacting protein (Human)	BDBM4293 ((2E)-3-(3,4-dihydroxyphenyl)-2-[(3,4-dihydroxyphen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Alkaline phosphatase, tissue-nonspecific isozyme (Human)	BDBM4293 ((2E)-3-(3,4-dihydroxyphenyl)-2-[(3,4-dihydroxyphen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM4293 ((2E)-3-(3,4-dihydroxyphenyl)-2-[(3,4-dihydroxyphen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
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Alkaline phosphatase, tissue-nonspecific isozyme (Human)	BDBM4293 ((2E)-3-(3,4-dihydroxyphenyl)-2-[(3,4-dihydroxyphen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.49E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Alkaline phosphatase, germ cell type (Human)	BDBM4293 ((2E)-3-(3,4-dihydroxyphenyl)-2-[(3,4-dihydroxyphen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	8.03E+3	n/a	n/a	n/a	n/a
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Intestinal-type alkaline phosphatase 1 (Rat)	BDBM4293 ((2E)-3-(3,4-dihydroxyphenyl)-2-[(3,4-dihydroxyphen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	259	n/a	n/a	n/a	n/a	n/a	n/a
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Intestinal-type alkaline phosphatase (Human)	BDBM4293 ((2E)-3-(3,4-dihydroxyphenyl)-2-[(3,4-dihydroxyphen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	6.36E+3	n/a	n/a	n/a	n/a
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Intestinal-type alkaline phosphatase (Human)	BDBM4293 ((2E)-3-(3,4-dihydroxyphenyl)-2-[(3,4-dihydroxyphen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.68E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Intestinal-type alkaline phosphatase 1 (Rat)	BDBM4293 ((2E)-3-(3,4-dihydroxyphenyl)-2-[(3,4-dihydroxyphen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Intestinal-type alkaline phosphatase (Human)	BDBM4293 ((2E)-3-(3,4-dihydroxyphenyl)-2-[(3,4-dihydroxyphen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.41E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase 33 (Human)	BDBM4293 ((2E)-3-(3,4-dihydroxyphenyl)-2-[(3,4-dihydroxyphen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.49E+4	n/a	n/a	n/a	n/a
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