BDBM4321 3-{[4-(2,2-dicyanoeth-1-en-1-yl)phenyl]carbamoyl}propanoic acid::benzylidenemalononitrile (BMN) deriv. 5

SMILES [#8]-[#6](=O)-[#6]-[#6]-[#6](=O)-[#7]-c1ccc(\[#6]=[#6](/C#N)C#N)cc1

InChI Key InChIKey=VNUISCLXMOOGIR-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 4321   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University Of Jerusalem

LigandPNGBDBM4321(3-{[4-(2,2-dicyanoeth-1-en-1-yl)phenyl]carbamoyl}p...)
Affinity DataKi:  2.40E+5nM ΔG°:  -4.89kcal/mole IC50:  6.40E+5nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed