BDBM435788 Methyl 2-methyl-3-(2-oxo-1,3-dihydrobenzimidazol-5-yl)benzoate;::US10611730, Example 46

SMILES COC(=O)c1cccc(-c2ccc3[nH]c(=O)[nH]c3c2)c1C

InChI Key InChIKey=CNKCLQDWRZSXOY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 435788   

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 435788BDBM435788(US10611730, Example 46 | Methyl 2-methyl-3-(2-oxo-...)
Affinity DataIC50: 50.1nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
US Patent