BDBM437446 4-Ethoxy-5-[1-(2-methanesulfonyl-phenyl)-1H-pyrazol-4- yl]-1-methyl-1H-pyridin-2-one::US10617680, Example 180::US11020380, Example 180

SMILES CCOc1cc(=O)n(C)cc1-c1cnn(c1)-c1ccccc1S(C)(=O)=O

InChI Key InChIKey=AYTSAQWYHOVNGE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437446   

TargetCREB-binding protein(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM437446(4-Ethoxy-5-[1-(2-methanesulfonyl-phenyl)-1H-pyrazo...)
Affinity DataIC50: <500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM437446(4-Ethoxy-5-[1-(2-methanesulfonyl-phenyl)-1H-pyrazo...)
Affinity DataIC50: <500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent