BDBM4663 4-Anilinoquinazoline 10::N-(4-Chloro-2-fluorophenyl)-6-methoxy-7-{[(2E)-4-pyrrolidin-1-ylbut-2-enyl]oxy}quinazolin-4-amine::N-(4-chloro-2-fluorophenyl)-6-methoxy-7-{[(2E)-4-(pyrrolidin-1-yl)but-2-en-1-yl]oxy}quinazolin-4-amine
SMILES COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1OC\C=C\CN1CCCC1
InChI Key InChIKey=BMEKKWWFQMYXPU-SNAWJCMRSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 4663
Affinity DataIC50: 750nMpH: 7.4 T: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room...More data for this Ligand-Target Pair
Affinity DataIC50: 90nMT: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit EGF-R RTK activity. The compounds were incubated with enzyme 20 min at room ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMT: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit FGFR-1 TK activity. The compounds were incubated with enzyme 20 min at room ...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMT: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room...More data for this Ligand-Target Pair