BDBM476979 peptidomimetic coronavirus 3CLpro inhibitors 17

SMILES CC(C)C[C@H](NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)C(=O)N(C)C

InChI Key InChIKey=MLMGWGFHIFVPAJ-MLCQCVOFSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 476979   

TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
A*Star

LigandPNGBDBM476979(peptidomimetic coronavirus 3CLpro inhibitors 17)
Affinity DataIC50:  7nMAssay Description:The assays are from references cited in this article.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
A*Star

LigandPNGBDBM476979(peptidomimetic coronavirus 3CLpro inhibitors 17)
Affinity DataIC50:  65nMAssay Description:SARS-CoV-2 3CLpro expression and purification is based on a published procedure and our modified protocol is found in the supplementary file. A highl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed