BDBM479496 ML300-based SC inhibitor 35
SMILES Clc1cccc(CN(C(=O)Cn2nnc3ccccc23)c2ccc(cc2)-c2ccc[nH]c2=O)c1
InChI Key InChIKey=OMFBUEFMMHUWOX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 479496
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Cleveland Clinic
Cleveland Clinic
Affinity DataIC50: 657nMAssay Description:The protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, end point assay adapted from a previ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.67E+4nMAssay Description:Confluent monolayers of Vero E6 ACE2 cells in 12-well plates were washed once with DMEM and infected with approximately 50 plaque forming units (PFUs...More data for this Ligand-Target Pair
Affinity DataEC50: 8.77E+3nMAssay Description:Briefly, Vero E6 ACE2 cells were cultured in 96-well flat-bottom plates at a density of 2 × 104 cells per well. Following infection of the cells with...More data for this Ligand-Target Pair
Affinity DataIC50: 746nMAssay Description:The protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, end point assay adapted from a previ...More data for this Ligand-Target Pair