BDBM4812 (3Z)-3-({3,5-dimethyl-4-[3-(4-methylpiperazin-1-yl)propyl]-1H-pyrrol-2-yl}methylidene)-2,3-dihydro-1H-indol-2-one::SU5416 analog 5c

SMILES: CN1CCN(CCCc2c(C)[nH]c(\C=C3/C(=O)Nc4ccccc34)c2C)CC1

InChI Key: InChIKey=LPLGZUZPKACGSS-UHFFFAOYSA-N

Data: 4 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 4812   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Human)	BDBM4812 ((3Z)-3-({3,5-dimethyl-4-[3-(4-methylpiperazin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	300	n/a	n/a	n/a	n/a	7.5	22
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Fibroblast growth factor receptor 1 (Human)	BDBM4812 ((3Z)-3-({3,5-dimethyl-4-[3-(4-methylpiperazin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	7.5	22
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Platelet-derived growth factor receptor beta (Human)	BDBM4812 ((3Z)-3-({3,5-dimethyl-4-[3-(4-methylpiperazin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM4812 ((3Z)-3-({3,5-dimethyl-4-[3-(4-methylpiperazin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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