BDBM484482 US10934294, Example 4::US11028092, Example 4

SMILES C[C@H](c1ccc(F)cc1)n1nc(C#N)c2c1nc([nH]c2=O)[C@H]1CC[C@@H]1c1ncccn1

InChI Key

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 484482   

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM484482(US10934294, Example 4 | US11028092, Example 4)
Affinity DataKi:  4.80nMAssay Description:Assays for PDE 1 through 11 were performed in parallel at room temperature in 384-well microtiter plates with an incubation volume of 20.2 μL. S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM484482(US10934294, Example 4 | US11028092, Example 4)
Affinity DataKi:  4.80nMAssay Description:Human PDE9 (PDE9A2, GenBank Accession No. NM_001001567), full length with N-terminal GST tag, was purchased from BPS Bioscience. The fluorescence pol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent