BDBM4918 3-(2-{[(3Z)-6-methoxy-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-4,5,6,7-tetrahydro-1H-indol-3-yl)propanoic acid::Indolin-2-one deriv. 9e

SMILES: COc1ccc2\C(=C\c3[nH]c4CCCCc4c3CCC(O)=O)C(=O)Nc2c1

InChI Key: InChIKey=QKVUBIOLQLJVKI-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 4918   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Human)	BDBM4918 (3-(2-{[(3Z)-6-methoxy-2-oxo-2,3-dihydro-1H-indol-3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	380	n/a	n/a	n/a	n/a	7.5	22
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Fibroblast growth factor receptor 1 (Human)	BDBM4918 (3-(2-{[(3Z)-6-methoxy-2-oxo-2,3-dihydro-1H-indol-3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.08E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM4918 (3-(2-{[(3Z)-6-methoxy-2-oxo-2,3-dihydro-1H-indol-3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor beta (Human)	BDBM4918 (3-(2-{[(3Z)-6-methoxy-2-oxo-2,3-dihydro-1H-indol-3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.93E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM4918 (3-(2-{[(3Z)-6-methoxy-2-oxo-2,3-dihydro-1H-indol-3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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