BDBM492271 5-[6-(tert-Butylamino)-4-(difluoromethyl)-3-pyridyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-tetrahydropyran-4-yl-thiazole-2-carboxamide::US10975068, Example 412

SMILES C[C@H]1CCCN1C(=O)c1nc(sc1-c1cnc(NC(C)(C)C)cc1C(F)F)C(=O)NC1CCOCC1

InChI Key InChIKey=CBXDIWZKXOCVHW-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 492271   

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM492271(5-[6-(tert-Butylamino)-4-(difluoromethyl)-3-pyridy...)
Affinity DataKd:  3.40nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
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Date in BDB:
10/20/2021
Entry Details
US Patent