BDBM496248 CVD-0013192::MAT-POS-b3e365b9-1

SMILES Clc1ccc2OCC[C@@H](C(=O)Nc3cncc4ccccc34)c2c1

InChI Key InChIKey=QRUNNMAOPKEFMJ-OAHLLOKOSA-N

Data  3 IC50

PDB links: 2 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 496248   

TargetReplicase polyprotein 1ab(2019-nCoV)
Israel Institution Of Biological Research

LigandPNGBDBM496248(CVD-0013192 | MAT-POS-b3e365b9-1)
Affinity DataIC50:  246nMAssay Description:The assay was performed according to the published procedure. Briefly, compounds were seeded into assay-ready plates (Greiner 384PP, cat# 781280) usi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PDB3D3D Structure (crystal)
TargetReplicase polyprotein 1ab(2019-nCoV)
Israel Institution Of Biological Research

LigandPNGBDBM496248(CVD-0013192 | MAT-POS-b3e365b9-1)
Affinity DataIC50:  209nMAssay Description:Compounds were seeded into assay-ready plates (Greiner 384 low volume, cat. no. 784900) using an Echo 555 acoustic dispenser, and dimethyl sulfoxide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetReplicase polyprotein 1ab(2019-nCoV)
Israel Institution Of Biological Research

LigandPNGBDBM496248(CVD-0013192 | MAT-POS-b3e365b9-1)
Affinity DataIC50:  190nMAssay Description:Compounds were seeded into assay-ready plates (Greiner 384 low volume, cat 784900) using an Echo 555 acoustic dispenser, and DMSO was back-filled for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PDB3D3D Structure (crystal)