BDBM497043 US11001561, Compound 36::US11702392, Compound 36

SMILES CCc1c(nc(C)n(-c2cccc(Cl)c2Cl)c1=O)N1CCC2(CO[C@@H](C)[C@H]2N)CC1

InChI Key InChIKey=NNOKAXLMQPCAFE-ORAYPTAESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 497043   

TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM497043(US11001561, Compound 36 | US11702392, Compound 36)
Affinity DataIC50:  5.00E+3nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM497043(US11001561, Compound 36 | US11702392, Compound 36)
Affinity DataIC50:  5.00E+3nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent