BDBM497055 US11001561, Compound 48::US11702392, Compound 48

SMILES Cc1nc(N2CCC(C)(N)CC2)c(C)c(=O)n1-c1ccc2ccccc2c1Cl

InChI Key InChIKey=AQNOMHOXRNYABP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 497055   

TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM497055(US11001561, Compound 48 | US11702392, Compound 48)
Affinity DataIC50:  1.80E+4nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM497055(US11001561, Compound 48 | US11702392, Compound 48)
Affinity DataIC50:  1.80E+4nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent