BDBM497101 US11001561, Compound 80a::US11001561, Compound 80c::US11001561, Compound 80d
SMILES Cc1nc(N2CCC3(CC2)Oc2cnccc2[C@@H]3N)c(C)c(=O)n1-c1cccc(Cl)c1Cl
InChI Key InChIKey=AIHIABMIEGWKTR-FQEVSTJZSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 497101
Affinity DataIC50: 1.40E+3nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair