BDBM497102 US11001561, Compound 80b

SMILES Cc1nc(N2CCC3(CC2)Oc2cnccc2[C@H]3N)c(C)c(=O)n1-c1cccc(Cl)c1Cl

InChI Key InChIKey=AIHIABMIEGWKTR-HXUWFJFHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 497102   

TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM497102(US11001561, Compound 80b)
Affinity DataIC50: >1.00E+4nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent