BDBM499885 (4-(((3R,6S)-6-((R)-1- hydroxyethyl)tetrahydro-2H-pyran-3- yl)amino)-7H-pyrrolo[2,3-d]pyrimidin- 5-yl)(2-methyl-4- phenoxyphenyl)methanone::US11020398, Compound I-197

SMILES C[C@@H](O)[C@@H]1CC[C@H](CO1)Nc1ncnc2[nH]cc(C(=O)c3ccc(Oc4ccccc4)cc3C)c12

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 499885   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Arqule

US Patent
LigandPNGBDBM499885((4-(((3R,6S)-6-((R)-1- hydroxyethyl)tetrahydro-2H-...)
Affinity DataIC50:  1.60nMAssay Description:The active BTK assay consisted of phosphorylated form of full length BTK. The assay was performed in a buffer solution utilized in the inactive BTK a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent