BDBM50000267 2-(3,4-Dichloro-phenyl)-1-(2-dimethylaminomethyl-piperidin-1-yl)-ethanone::2-(3,4-Dichloro-phenyl)-1-(2-dimethylaminomethyl-piperidin-1-yl)-ethanone(HCl)::CHEMBL339552

SMILES CN(C)CC1CCCCN1C(=O)Cc1ccc(Cl)c(Cl)c1

InChI Key InChIKey=PROCBUWEYFCOPD-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50000267   

TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Zambeletti Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50000267(2-(3,4-Dichloro-phenyl)-1-(2-dimethylaminomethyl-p...)
Affinity DataKi:  1.40nMAssay Description:Compound was evaluated for its binding affinity against Opioid receptor kappa 1 subtype in guinea pig brain (minus cerebellum)using [3H]-U-69,593 as ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Zambeletti Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50000267(2-(3,4-Dichloro-phenyl)-1-(2-dimethylaminomethyl-p...)
Affinity DataKi:  3.05E+3nMAssay Description:Compound was evaluated for its binding affinity against Opioid receptor mu 1 subtype in guinea pig brain (minus cerebellum) using [3H]-DAGO as radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000267(2-(3,4-Dichloro-phenyl)-1-(2-dimethylaminomethyl-p...)
Affinity DataIC50:  102nMAssay Description:Opioid receptor kappa 1 agonist potency of the compound was determined in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed