BDBM50000270 2-(3,4-Dichloro-phenyl)-1-(3-hydroxy-2-pyrrolidin-1-ylmethyl-piperidin-1-yl)-ethanone::CHEMBL146632

SMILES O[C@@H]1CCCN([C@@H]1CN1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1

InChI Key InChIKey=PMJJKBYEMSFUBW-IAGOWNOFSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50000270   

TargetKappa-type opioid receptor(Homo sapiens (Human))
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000270(2-(3,4-Dichloro-phenyl)-1-(3-hydroxy-2-pyrrolidin-...)
Affinity DataIC50:  590nMAssay Description:Opioid receptor kappa agonist potency was determined in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed