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BDBM50000402 5-(1-Carboxy-2-phenyl-ethyl)-pyridine-2-carboxylic acid::CHEMBL355886

SMILES: OC(=O)C(Cc1ccccc1)c1ccc(nc1)C(O)=O

InChI Key: InChIKey=ODAGOQCTPRRXEW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50000402   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hypoxia-inducible factor prolyl hydroxylase 4 (HIF)


(Homo sapiens (Human))
BDBM50000402
PNG
(5-(1-Carboxy-2-phenyl-ethyl)-pyridine-2-carboxylic...)
Show SMILES OC(=O)C(Cc1ccccc1)c1ccc(nc1)C(O)=O
Show InChI InChI=1S/C15H13NO4/c17-14(18)12(8-10-4-2-1-3-5-10)11-6-7-13(15(19)20)16-9-11/h1-7,9,12H,8H2,(H,17,18)(H,19,20)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.70E+4n/an/an/an/an/an/a



ICI Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of prolyl 4-hydroxylase


J Med Chem 35: 800-4 (1992)


Article DOI: 10.1021/jm00083a001
BindingDB Entry DOI: 10.7270/Q25T3M3C
More data for this
Ligand-Target Pair