BDBM50000573 6-{6-[2-(2-Hydroxy-ethyl)-piperidin-4-yl]-hexyloxy}-2-phenyl-chromen-4-one::CHEMBL39713

SMILES OCCC1CC(CCCCCCOc2ccc3oc(cc(=O)c3c2)-c2ccccc2)CCN1

InChI Key InChIKey=ILHCFXHHSGJCMQ-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50000573   

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50000573(6-{6-[2-(2-Hydroxy-ethyl)-piperidin-4-yl]-hexyloxy...)
Affinity DataKi:  2.70E+3nMAssay Description:Affinity towards dopamine receptor D2 was determined by competition studies using [3H]-sulpiride in rat striatum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50000573(6-{6-[2-(2-Hydroxy-ethyl)-piperidin-4-yl]-hexyloxy...)
Affinity DataIC50:  16nMAssay Description:Potency at the sigma binding site was determined in radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50000573(6-{6-[2-(2-Hydroxy-ethyl)-piperidin-4-yl]-hexyloxy...)
Affinity DataIC50:  68nMAssay Description:Potency at the sigma binding site was determined in radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed