BDBM50000604 6-[6-(4-Hydroxy-piperidin-1-yl)-hexyloxy]-2-thiophen-2-yl-chromen-4-one::CHEMBL36928

SMILES OC1CCN(CCCCCCOc2ccc3oc(cc(=O)c3c2)-c2cccs2)CC1

InChI Key InChIKey=IYZKNKNHPCKKSN-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50000604   

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50000604(6-[6-(4-Hydroxy-piperidin-1-yl)-hexyloxy]-2-thioph...)
Affinity DataKi:  4.00E+3nMAssay Description:Affinity towards dopamine receptor D2 site was determined by competition studies using [3H]-sulpiride in rat striatum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50000604(6-[6-(4-Hydroxy-piperidin-1-yl)-hexyloxy]-2-thioph...)
Affinity DataIC50:  232nMAssay Description:Potency at the sigma binding site was determined in radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50000604(6-[6-(4-Hydroxy-piperidin-1-yl)-hexyloxy]-2-thioph...)
Affinity DataIC50:  119nMAssay Description:Potency at the sigma binding site was determined in radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed