BDBM50000824 2-[3-Fluoro-5-(4-methoxy-tetrahydro-pyran-4-yl)-phenoxymethyl]-quinazoline; compound with acetic acid ethyl ester::CHEMBL87032

SMILES COC1(CCOCC1)c1cc(F)cc(OCc2ncc3ccccc3n2)c1

InChI Key InChIKey=DKYBYGHHMXNNRM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50000824   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000824(2-[3-Fluoro-5-(4-methoxy-tetrahydro-pyran-4-yl)-ph...)
Affinity DataIC50:  200nMAssay Description:In vitro inhibition of leukotriene B4 synthesis in human whole blood by inhibiting 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed