BDBM50001405 1'-(4-methylphenylsulfonyl)spiro[1H-indene-1,4'-(hexahydropyridine)]::CHEMBL341490

SMILES Cc1ccc(cc1)S(=O)(=O)N1CCC2(CC1)C=Cc1ccccc21

InChI Key InChIKey=VRVIZJNFYYAUKC-UHFFFAOYSA-N

Data  4 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50001405   

TargetOxytocin receptor(Homo sapiens (Human))
Drugmoldesign

Curated by ChEMBL
LigandPNGBDBM50001405(1'-(4-methylphenylsulfonyl)spiro[1H-indene-1,4'-(h...)
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [3H]-oxytocin from oxytocin receptor in human uterus tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(RAT)
Drugmoldesign

Curated by ChEMBL
LigandPNGBDBM50001405(1'-(4-methylphenylsulfonyl)spiro[1H-indene-1,4'-(h...)
Affinity DataKi:  1.60E+3nMAssay Description:Displacement of [3H]-oxytocin from oxytocin receptor in rat uterus tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(RAT)
Drugmoldesign

Curated by ChEMBL
LigandPNGBDBM50001405(1'-(4-methylphenylsulfonyl)spiro[1H-indene-1,4'-(h...)
Affinity DataKi:  9.80E+3nMAssay Description:Displacement of [3H]-vasopressin from vasopressin V1a receptor in rat liver tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Rattus norvegicus (Rat))
Drugmoldesign

Curated by ChEMBL
LigandPNGBDBM50001405(1'-(4-methylphenylsulfonyl)spiro[1H-indene-1,4'-(h...)
Affinity DataKi: >4.00E+4nMAssay Description:Displacement of [3H]-vasopressin from vasopressin V2 receptor in rat kidney tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b/V2 receptor(RAT)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50001405(1'-(4-methylphenylsulfonyl)spiro[1H-indene-1,4'-(h...)
Affinity DataIC50:  3.50E+4nMAssay Description:Half-maximal inhibition of binding of [3H]vasopressin to vasopressin receptor 1 in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a/V1b/V2 receptor(RAT)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50001405(1'-(4-methylphenylsulfonyl)spiro[1H-indene-1,4'-(h...)
Affinity DataIC50:  1.00E+5nMAssay Description:Half-maximal inhibition of binding of [3H]- vasopressin to the vasopressin receptor 2 in rat kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(RAT)
Drugmoldesign

Curated by ChEMBL
LigandPNGBDBM50001405(1'-(4-methylphenylsulfonyl)spiro[1H-indene-1,4'-(h...)
Affinity DataIC50:  4.00E+3nMAssay Description:Half-maximal inhibition of binding of [3H]-Oxytocin to OT receptor in rat uterine tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed