BDBM50001634 8-(4,6-Diphenyl-pyridin-2-yloxy)-2,2-dimethyl-octanoic acid::CHEMBL135612

SMILES CC(C)(CCCCCCOc1cc(cc(n1)-c1ccccc1)-c1ccccc1)C(O)=O

InChI Key InChIKey=WFPFILGYCCUVGQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50001634   

TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Centre De Recherche De Vitry-Alfortville

Curated by ChEMBL
LigandPNGBDBM50001634(8-(4,6-Diphenyl-pyridin-2-yloxy)-2,2-dimethyl-octa...)
Affinity DataIC50:  60nMAssay Description:Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Centre De Recherche De Vitry-Alfortville

Curated by ChEMBL
LigandPNGBDBM50001634(8-(4,6-Diphenyl-pyridin-2-yloxy)-2,2-dimethyl-octa...)
Affinity DataIC50:  100nMAssay Description:Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Centre De Recherche De Vitry-Alfortville

Curated by ChEMBL
LigandPNGBDBM50001634(8-(4,6-Diphenyl-pyridin-2-yloxy)-2,2-dimethyl-octa...)
Affinity DataIC50:  22nMAssay Description:Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed