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BDBM50001640 6-(4,6-Diphenyl-pyridin-2-yloxy)-hexanoic acid amide::CHEMBL136953

SMILES: NC(=O)CCCCCOc1cc(cc(n1)-c1ccccc1)-c1ccccc1

InChI Key: InChIKey=TWPWFLNKGCYTGP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50001640   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Leukotriene B4 receptor


(HUMAN)
BDBM50001640
PNG
(6-(4,6-Diphenyl-pyridin-2-yloxy)-hexanoic acid ami...)
Show SMILES NC(=O)CCCCCOc1cc(cc(n1)-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C23H24N2O2/c24-22(26)14-8-3-9-15-27-23-17-20(18-10-4-1-5-11-18)16-21(25-23)19-12-6-2-7-13-19/h1-2,4-7,10-13,16-17H,3,8-9,14-15H2,(H2,24,26)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 150n/an/an/an/an/an/a



Centre de Recherche de Vitry-Alfortville

Curated by ChEMBL


Assay Description
Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.


J Med Chem 35: 4315-24 (1992)


Article DOI: 10.1021/jm00101a008
BindingDB Entry DOI: 10.7270/Q2QR4W2W
More data for this
Ligand-Target Pair
LTB4R


(HUMAN)
BDBM50001640
PNG
(6-(4,6-Diphenyl-pyridin-2-yloxy)-hexanoic acid ami...)
Show SMILES NC(=O)CCCCCOc1cc(cc(n1)-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C23H24N2O2/c24-22(26)14-8-3-9-15-27-23-17-20(18-10-4-1-5-11-18)16-21(25-23)19-12-6-2-7-13-19/h1-2,4-7,10-13,16-17H,3,8-9,14-15H2,(H2,24,26)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 160n/an/an/an/an/an/a



Centre de Recherche de Vitry-Alfortville

Curated by ChEMBL


Assay Description
Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.


J Med Chem 35: 4315-24 (1992)


Article DOI: 10.1021/jm00101a008
BindingDB Entry DOI: 10.7270/Q2QR4W2W
More data for this
Ligand-Target Pair