BDBM50003821 6-[4,5-Bis-(4-methoxy-phenyl)-1H-imidazol-2-ylsulfanylmethyl]-4-hydroxy-4-methyl-tetrahydro-pyran-2-one::CHEMBL337377

SMILES COc1ccc(cc1)-c1nc(SCC2C[C@](C)(O)CC(=O)O2)[nH]c1-c1ccc(OC)cc1

InChI Key InChIKey=FHPJAMPPGLDSTR-WIIYFNMSSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50003821   

TargetSterol O-acyltransferase 1(Rattus norvegicus)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50003821(6-[4,5-Bis-(4-methoxy-phenyl)-1H-imidazol-2-ylsulf...)
Affinity DataIC50:  420nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed