BDBM50003903 CHEMBL3235332

SMILES CC1(C)Cc2c(c3CCNCc3n2-c2ccc(cc2)C(N)=O)C(=O)C1

InChI Key InChIKey=QEIFWHGXYQFXRO-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50003903   

TargetHeat shock protein HSP 90-beta(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50003903(CHEMBL3235332)
Affinity DataKi:  1.50E+3nMAssay Description:Displacement of FITC-geldanamycin from recombinant HSP90beta (unknown origin) after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50003903(CHEMBL3235332)
Affinity DataKi:  1.90E+3nMAssay Description:Displacement of FITC-geldanamycin from recombinant HSP90alpha (unknown origin) after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50003903(CHEMBL3235332)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of FITC-geldanamycin from recombinant TRAP1 (unknown origin) after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetEndoplasmin(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50003903(CHEMBL3235332)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of FITC-geldanamycin from recombinant GRP94 (unknown origin) after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed