BDBM50005835 (3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methylmethanesulfonamide::1-[3-(2-dimethylaminoethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide::1-{3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}-N-methylmethanesulfonamide::3-(2-(dimethylamino)ethyl)-N-methyl-1H-indole-5-methanesulfonamide::3-[2-(dimethylamino)ethyl]-N-methylindole-5-methanesulfonamide::CHEMBL128::SUMATRIPTAN::Sumatran::Sumax
SMILES CNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1
InChI Key InChIKey=KQKPFRSPSRPDEB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 186 hits for monomerid = 50005835
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]5-hydroxytryptamine from human cloned 5HT1D receptor expressed in CHOK1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:The compound was tested for CNS binding affinity towards 5-hydroxytryptamine 1D receptor from cloned gorilla membranes expressed in cultured HEK 293 ...More data for this Ligand-Target Pair
Affinity DataKi: 3.40nMAssay Description:Binding affinity towards cloned human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3.40nMAssay Description:Binding affinity of the compound was evaluated at the cloned human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4.40nMAssay Description:In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
Affinity DataKi: 5.5nMAssay Description:Binding affinity for human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
Affinity DataKi: 5.5nMAssay Description:Binding affinity was measured on 5-hydroxytryptamine 1D receptor beta in CHO cells transfected with human 5-HT1D beta gene labeled with [3H]-5-HTMore data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Compound was tested for binding affinity against cloned human 5-hydroxytryptamine 1D receptor alpha expressed in CHO-K1 cells.More data for this Ligand-Target Pair
Affinity DataKi: 6.40nMAssay Description:The compound was tested for CNS binding affinity towards 5-hydroxytryptamine 1B receptor from cloned gorilla membranes expressed in cultured HEK 293 ...More data for this Ligand-Target Pair
Affinity DataKi: 7.70nMAssay Description:Binding affinity towards cloned human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
Affinity DataKi: 7.70nMAssay Description:Binding affinity of the compound was evaluated at the cloned human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
Affinity DataKi: 8.5nMAssay Description:Binding affinity towards cloned human 5-hydroxytryptamine 1D receptor alpha was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 8.5nMAssay Description:Binding affinity to recombinant human 5-hydroxytryptamine 1D receptor alphaMore data for this Ligand-Target Pair
Affinity DataKi: 8.5nMAssay Description:Ability to inhibit the forskolin-stimulated c-AMP formation mediated by human 5-hydroxytryptamine 1D receptor in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 8.60nMAssay Description:In vitro binding affinity was determined towards cloned human 5-hydroxytryptamine 1D receptor using [3H]-5-CT radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 9.10nMAssay Description:Displacement of [3H]5-hydroxytryptamine from human cloned 5HT1B receptor expressed in CHOK1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 9.60nMAssay Description:In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Binding affinity for recombinant human 5-hydroxytryptamine 1D receptor beta was determined using [3H]-5-HT as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Binding affinity for human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:In vitro binding affinity was determined towards cloned human 5-hydroxytryptamine 1B receptor using [3H]-5-CT radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:Compound was tested for binding affinity against cloned human 5-hydroxytryptamine 1D receptor beta expressed in CHO-K1 cells.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Rat)
Medical College of Virginia/Virginia Commonwealth University
Curated by ChEMBL
Medical College of Virginia/Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 23nMAssay Description:Binding affinity was measured on 5-hydroxytryptamine 1B receptor in rat striatum labeled with [3H]-5-HTMore data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:The compound was tested for binding affinity against cloned human 5-hydroxytryptamine 1D receptor betaMore data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Binding affinity towards cloned human 5-hydroxytryptamine 1D receptor beta was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 23.1nMAssay Description:Ability to inhibit the forskolin-stimulated c-AMP formation mediated by human 5-hydroxytryptamine 1B receptor in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:Compound was tested for intrinsic efficacy against human 5-hydroxytryptamine 1D receptor beta measured as the reduction of forskolin-stimulated cAMP.More data for this Ligand-Target Pair
Affinity DataKi: 25.7nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 1F receptor was determinedMore data for this Ligand-Target Pair