BDBM50006686 2-{2,5-Difluoro-4-[(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid ;hydrate(0.5H2O)::CHEMBL73902

SMILES Cc1nc2ccc(CN(CC#C)c3cc(F)c(cc3F)C(=O)N[C@@H](CCC(O)=O)C(O)=O)cc2c(=O)[nH]1

InChI Key InChIKey=DZFXSEGBQJGJOL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50006686   

TargetThymidylate synthase(Mus musculus)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50006686(2-{2,5-Difluoro-4-[(2-methyl-4-oxo-3,4-dihydro-qui...)
Affinity DataIC50:  600nMAssay Description:Inhibition of thymidylate synthase from L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed