BDBM50006977 CHEMBL55317::Indan-2-yl-(3-phenyl-propyl)-amine

SMILES C(CNC1Cc2ccccc2C1)Cc1ccccc1

InChI Key InChIKey=HQOMLTLQWBDVRA-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50006977   

TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50006977(CHEMBL55317 | Indan-2-yl-(3-phenyl-propyl)-amine)
Affinity DataKi:  27nMAssay Description:Inhibition of [3H]DTG binding to Sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50006977(CHEMBL55317 | Indan-2-yl-(3-phenyl-propyl)-amine)
Affinity DataKi:  38nMAssay Description:Displacement of [3H]DTG from sigma 2 receptor in rat liver membranes incubated for 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50006977(CHEMBL55317 | Indan-2-yl-(3-phenyl-propyl)-amine)
Affinity DataKi:  58nMAssay Description:Displacement of [3H]-(+)-pentazocine from Sigma1 receptor in guinea pig cortex membranes incubated for 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50006977(CHEMBL55317 | Indan-2-yl-(3-phenyl-propyl)-amine)
Affinity DataKi:  117nMAssay Description:Displacement of [3H]ifenprodil from human GluN2B expressed in mouse L(tk-) cell membranes co-expressing GluN1a incubated for 2 hrs by scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed