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BDBM50007292 CHEMBL101774::Sodium; 6-{2-[1-(4-fluoro-phenyl)-3-methyl-butyl]-4,6-dimethyl-phenoxy}-3,5-dihydroxy-hexanoate

SMILES: CC(C)CC(c1ccc(F)cc1)c1cc(C)cc(C)c1OCC(O)C[C@@H](O)CC([O-])=O

InChI Key: InChIKey=YXCVOFSBSRBCGH-ITAUSPCMSA-M

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50007292   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
HMG-CoA reductase


(Rattus norvegicus (rat))
BDBM50007292
PNG
(CHEMBL101774 | Sodium; 6-{2-[1-(4-fluoro-phenyl)-3...)
Show SMILES CC(C)CC(c1ccc(F)cc1)c1cc(C)cc(C)c1OCC(O)C[C@@H](O)CC([O-])=O
Show InChI InChI=1S/C25H33FO5/c1-15(2)9-22(18-5-7-19(26)8-6-18)23-11-16(3)10-17(4)25(23)31-14-21(28)12-20(27)13-24(29)30/h5-8,10-11,15,20-22,27-28H,9,12-14H2,1-4H3,(H,29,30)/p-1/t20-,21?,22?/m1/s1
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MMDB

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Similars

Article
PubMed
n/an/a 140n/an/an/an/an/an/a



Hoechst AG

Curated by ChEMBL


Assay Description
In vitro inhibition of HMG-CoA reductase in solubilized rat liver.


J Med Chem 34: 2962-83 (1991)


Article DOI: 10.1021/jm00114a004
BindingDB Entry DOI: 10.7270/Q2C829WX
More data for this
Ligand-Target Pair