BDBM50007292 CHEMBL101774::Sodium; 6-{2-[1-(4-fluoro-phenyl)-3-methyl-butyl]-4,6-dimethyl-phenoxy}-3,5-dihydroxy-hexanoate

SMILES CC(C)CC(c1ccc(F)cc1)c1cc(C)cc(C)c1OCC(O)C[C@@H](O)CC([O-])=O

InChI Key InChIKey=YXCVOFSBSRBCGH-ITAUSPCMSA-M

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50007292   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Hoechst

Curated by ChEMBL
LigandPNGBDBM50007292(CHEMBL101774 | Sodium; 6-{2-[1-(4-fluoro-phenyl)-3...)
Affinity DataIC50:  140nMAssay Description:In vitro inhibition of HMG-CoA reductase in solubilized rat liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed