BDBM50007456 1-[4-(8-Methoxy-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-ethanone::CHEMBL131155

SMILES [#6]-[#8]-c1ccc2c(-[#6]-[#6]-c3cccnc3\[#6]-2=[#6]-2\[#6]-[#6]-[#7](-[#6]-[#6]-2)-[#6](-[#6])=O)c1

InChI Key InChIKey=LDENPNCRFIDJLK-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50007456   

TargetHistamine H1 receptor(RAT)
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50007456(1-[4-(8-Methoxy-5,6-dihydro-benzo[5,6]cyclohepta[1...)
Affinity DataKi:  1.60E+3nMAssay Description:Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50007456(1-[4-(8-Methoxy-5,6-dihydro-benzo[5,6]cyclohepta[1...)
Affinity DataIC50:  5.60E+4nMAssay Description:Inhibitory activity against recombinant human farnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Homo sapiens (Human))
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50007456(1-[4-(8-Methoxy-5,6-dihydro-benzo[5,6]cyclohepta[1...)
Affinity DataIC50:  3.40E+3nMAssay Description:Concentration required to cause 50% inhibition of platelet activating factor (PAF)-induced platelet aggregation of human platelet rich plasma when ch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed