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BDBM50008060 8-Acetyl-3-benzoyloxy-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester::CHEMBL288315

SMILES: COC(=O)C1C2CC[C@H](CC1OC(=O)c1ccccc1)N2C(C)=O

InChI Key: InChIKey=OHUOYIUXXBLSTC-JYLOXXHMSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50008060   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine Transporter (DAT)


(Rattus norvegicus (rat))
BDBM50008060
PNG
(8-Acetyl-3-benzoyloxy-8-aza-bicyclo[3.2.1]octane-2...)
Show SMILES COC(=O)C1C2CC[C@H](CC1OC(=O)c1ccccc1)N2C(C)=O
Show InChI InChI=1S/C18H21NO5/c1-11(20)19-13-8-9-14(19)16(18(22)23-2)15(10-13)24-17(21)12-6-4-3-5-7-12/h3-7,13-16H,8-10H2,1-2H3/t13-,14?,15?,16?/m1/s1
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PC sid
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Similars

Article
PubMed
n/an/a 3.37E+3n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]3-beta-(p-fluorophenyl)tropane-2beta-carboxylic acid methyl ester [3H]7a binding to Dopamine transporter of rat striatal membranes


J Med Chem 35: 141-4 (1992)


Article DOI: 10.1021/jm00079a018
BindingDB Entry DOI: 10.7270/Q29Z95H8
More data for this
Ligand-Target Pair