BDBM50008123 5-Cyclohexyl-2,2-difluoro-4-{3-(1H-imidazol-4-yl)-2-[2-(morpholine-4-sulfonylamino)-3-phenyl-propionylamino]-propionylamino}-3-oxo-pentanoic acid (2-morpholin-4-yl-ethyl)-amide; Hydrate::CHEMBL262107

SMILES FC(F)(C(=O)NCCN1CCOCC1)C(=O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NS(=O)(=O)N1CCOCC1

InChI Key InChIKey=WTKGBRNASVNILX-CHQNGUEUSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50008123   

TargetCathepsin D(Bos taurus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50008123(5-Cyclohexyl-2,2-difluoro-4-{3-(1H-imidazol-4-yl)-...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory activity against bovine Cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50008123(5-Cyclohexyl-2,2-difluoro-4-{3-(1H-imidazol-4-yl)-...)
Affinity DataIC50:  0.900nMAssay Description:The concentration producing 50% inhibition of renin activity in monkey plasma was determined by radioimmunoassay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed