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BDBM50008685 1-Amino-13-ethylidene-11-methyl-6-aza-tricyclo[7.3.1.0*2,7*]trideca-2(7),3-dien-5-one::CHEMBL115350

SMILES: C\C=C1/C2CC(C)C[C@]1(N)c1ccc(=O)[nH]c1C2

InChI Key: InChIKey=PWWSISOORXDCMX-IKXKKEHFSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50008685   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Acetylcholinesterase


(Rattus norvegicus (rat))
BDBM50008685
PNG
(1-Amino-13-ethylidene-11-methyl-6-aza-tricyclo[7.3...)
Show SMILES C\C=C1/C2CC(C)C[C@]1(N)c1ccc(=O)[nH]c1C2
Show InChI InChI=1S/C15H20N2O/c1-3-11-10-6-9(2)8-15(11,16)12-4-5-14(18)17-13(12)7-10/h3-5,9-10H,6-8,16H2,1-2H3,(H,17,18)/b11-3+/t9?,10?,15-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.63E+3n/an/an/an/an/an/a



Mayo Clinic Jacksonville

Curated by ChEMBL


Assay Description
Compound was tested for its ability to inhibit the action of acetylcholinesterase isolated from rat brain cortex


J Med Chem 34: 3399-402 (1992)


Article DOI: 10.1021/jm00116a010
BindingDB Entry DOI: 10.7270/Q2TB17HH
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))
BDBM50008685
PNG
(1-Amino-13-ethylidene-11-methyl-6-aza-tricyclo[7.3...)
Show SMILES C\C=C1/C2CC(C)C[C@]1(N)c1ccc(=O)[nH]c1C2
Show InChI InChI=1S/C15H20N2O/c1-3-11-10-6-9(2)8-15(11,16)12-4-5-14(18)17-13(12)7-10/h3-5,9-10H,6-8,16H2,1-2H3,(H,17,18)/b11-3+/t9?,10?,15-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.63E+3n/an/an/an/an/an/a



Mayo Clinic Jacksonville

Curated by ChEMBL


Assay Description
Compound was tested for its ability to inhibit the action of acetylcholinesterase isolated from rat brain cortex


J Med Chem 34: 3399-402 (1992)


Article DOI: 10.1021/jm00116a010
BindingDB Entry DOI: 10.7270/Q2TB17HH
More data for this
Ligand-Target Pair