BDBM50008853 2-Bromo-4,5-dihydro-3H-naphtho[1,8-bc]thiophene-5-carboxylic acid methyl-(7-pyrrolidin-1-yl-1-oxa-spiro[4.5]dec-8-yl)-amide; compound with toluene-4-sulfonic acid::CHEMBL300832

SMILES CN([C@H]1CCC2(CCCO2)C[C@@H]1N1CCCC1)C(=O)C1CCc2c(Br)sc3cccc1c23

InChI Key InChIKey=WPDLVWOUMWRXIF-UGWRYHMVSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50008853   

TargetMu-type opioid receptor(GUINEA PIG)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008853(2-Bromo-4,5-dihydro-3H-naphtho[1,8-bc]thiophene-5-...)
Affinity DataKi:  170nMAssay Description:Compound was evaluated for the opioid receptor mu affinity determined with [3H][D-Ala2-MePhe4-Gly-ol5]-enkephalin (DAGOL) in the presence of excess u...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008853(2-Bromo-4,5-dihydro-3H-naphtho[1,8-bc]thiophene-5-...)
Affinity DataKi:  170nMAssay Description:Compound was evaluated for the opioid receptor mu affinity determined with [3H][D-Ala2-MePhe4-Gly-ol5]-enkephalin (DAGOL) in the presence of excess u...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008853(2-Bromo-4,5-dihydro-3H-naphtho[1,8-bc]thiophene-5-...)
Affinity DataKi:  272nMAssay Description:Opioid receptor kappa affinity, determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-enkephalinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008853(2-Bromo-4,5-dihydro-3H-naphtho[1,8-bc]thiophene-5-...)
Affinity DataKi:  272nMAssay Description:Opioid receptor kappa affinity, determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-enkephalinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed