BDBM50008986 2-(1-Naphthalen-1-yl-ethyl)-1,2-dihydro-indazol-3-one::CHEMBL3144575

SMILES C[C@H](c1cccc2ccccc12)n1[nH]c2ccccc2c1=O

InChI Key InChIKey=AOOSKFQNKDXJCS-ZDUSSCGKSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50008986   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50008986(2-(1-Naphthalen-1-yl-ethyl)-1,2-dihydro-indazol-3-...)
Affinity DataIC50:  1.40E+3nMAssay Description:In vitro inhibition of LTB4 production was measured in rat bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50008986(2-(1-Naphthalen-1-yl-ethyl)-1,2-dihydro-indazol-3-...)
Affinity DataEC50: >3.46E+5nMAssay Description:Ex vivo inhibition of LTB4 production was measured in dog bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50008986(2-(1-Naphthalen-1-yl-ethyl)-1,2-dihydro-indazol-3-...)
Affinity DataIC50:  4.00E+5nMAssay Description:In vitro inhibition of PGE-2 production was measured in rat bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed