BDBM50009001 5,6,7-Trihydroxyflavone::5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one::Baicalein::Baicalein, 14::Baicalein, 8::CHEMBL8260::US10252984, Table 2.33

SMILES: c1ccc(cc1)C2=CC(=O)c3c(cc(c(c3O)O)O)O2

InChI Key: InChIKey=FXNFHKRTJBSTCS-UHFFFAOYSA-N

Data: 5 KI  82 IC50  3 Kd  5 EC50

PDB links: 7 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 108 hits for monomerid = 50009001   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-coupled receptor kinase 6 (Human)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3 (Human)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.30E+3	n/a	n/a	n/a	n/a	7.45	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Linoleate 9S-lipoxygenase-4 (Soybean)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	8.0	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX12 (Human)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	8.0	23
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Human)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.15E+4	n/a	n/a	n/a	n/a	7.5	23
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15B (Human)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.10E+4	n/a	n/a	n/a	n/a	7.5	23
TBA									Citation and Details
					More data for this Ligand-Target Pair
1-deoxy-D-xylulose 5-phosphate reductoisomerase (Escherichia coli (strain K12))	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aurora kinase B (Human)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15B (Human)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	7.3	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Human)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	850	n/a	n/a	n/a	n/a	7.3	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Sheep)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	8.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Seed linoleate 13S-lipoxygenase-1 (Soybean)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.26E+4	n/a	n/a	n/a	n/a	8.0	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.94E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	940	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bovine)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.15E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Rat)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rat)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15B (Rat)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Trypsin (Human)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.91E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein phosphatase S (Human)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Human)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha 3 (Human)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Yes (Human)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fructose-1,6-bisphosphatase 1 (Human)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-synuclein (Human)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Progesterone receptor (Human)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	940	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	940	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	940	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Human)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK2 (Human)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.14E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK3 (Human)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.13E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.69E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	940	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.15E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.24E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	940	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3 (Human)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.86E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.06E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	980	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM50009001 (CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	940	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair