BDBM50009622 CHEMBL327709::[1-(4-Cyclohexylmethyl-3-hydroxy-2,6,10-trioxo-1-oxa-5,9-diaza-cyclotridec-7-ylcarbamoyl)-2-phenyl-ethyl]-carbamic acid tert-butyl ester

SMILES CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H]1CNC(=O)CCCOC(=O)[C@H](O)[C@H](CC2CCCCC2)NC1=O

InChI Key InChIKey=KEHJFSADHYLALA-JAYJDBRPSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50009622   

TargetRenin(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009622(CHEMBL327709 | [1-(4-Cyclohexylmethyl-3-hydroxy-2,...)
Affinity DataIC50:  9.20E+3nMpH: 7.4Assay Description:The compound was evaluated in vitro for inhibition of human plasma renin at pH 7.4.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed