BDBM50009835 4-Hydroxy-5-oxo-1-pyridin-4-ylmethyl-2,5-dihydro-1H-pyrrole-3-carboxylic acid ethyl ester::CHEMBL266773

SMILES CCOC(=O)C1CN(Cc2ccncc2)C(=O)C1=O

InChI Key InChIKey=GOEUHBJSLVMWJJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50009835   

TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009835(4-Hydroxy-5-oxo-1-pyridin-4-ylmethyl-2,5-dihydro-1...)
Affinity DataIC50:  110nMAssay Description:Percent inhibition of sorbitol accumulation in rat lens was measuredChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009835(4-Hydroxy-5-oxo-1-pyridin-4-ylmethyl-2,5-dihydro-1...)
Affinity DataIC50:  200nMAssay Description:In vitro inhibition of human placental aldose reductase.Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed