BDBM50009859 (+-)-2-(p-isobutylphenyl)propionic acid::(+-)-alpha-methyl-4-(2-methylpropyl)benzeneacetic acid::(+-)-ibuprofen::(+-)-p-isobutylhydratropic acid::(4-isobutylphenyl)-alpha-methylacetic acid::(RS)-ibuprofen::2-(4-isobutylphenyl)propanoic acid::2-[4-(2-methylpropyl)phenyl]propanoic acid::4-isobutylhydratropic acid::Advil::Brufen::CHEMBL521::IBUPROFEN LYSINE::Ibuprofen::Ibuprofen (1)::Motrin::alpha-(4-isobutylphenyl)propionic acid::alpha-(p-isobutylphenyl)propionic acid

SMILES: CC(C)Cc1ccc(cc1)[C@H](C)C(=O)O

InChI Key: InChIKey=HEFNNWSXXWATRW-UHFFFAOYSA-N

Data: 22 KI  141 IC50  2 Kd

PDB links: 14 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 165 hits for monomerid = 50009859   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 1 (Sheep)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	8.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	8.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Sheep)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 [E165G] (Human)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Caspase-3 (Human)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>6.60E+4	n/a	n/a	n/a	n/a	7.4	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Caspase-4 (Human)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a	7.4	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Caspase-5 (Human)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.10E+3	n/a	n/a	n/a	n/a	7.4	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Caspase-9 (Human)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	7.4	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rat)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.34E+5	n/a	n/a	n/a	n/a	7.0	4
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rat)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.63E+5	n/a	n/a	n/a	n/a	7.0	4
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>7.89E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acid-sensing ion channel 1 (Rat)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.13E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acid-sensing ion channel 1 (Rat)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.13E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acid-sensing ion channel 1 (Rat)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.35E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acid-sensing ion channel 3 (Rat)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.13E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acid-sensing ion channel 1 (Rat)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.95E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acid-sensing ion channel 1 (Rat)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.95E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acid-sensing ion channel 1 (Rat)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.95E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acid-sensing ion channel 1 (Rat)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.35E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (Rat)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.45E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Sheep)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.28E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Sheep)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.08E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (Rat)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rat)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Sheep)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Sheep)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Sheep)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Seed linoleate 13S-lipoxygenase-1 (Soybean)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Human)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Human)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.86E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Sheep)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Human)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.11E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rat)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Human)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Human)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Human)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Sheep)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Human)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.35E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cholinesterase (Human)	BDBM50009859 ((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<6.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair