BDBM50010031 2-(3-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-propyl)-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL84346

SMILES Fc1ccc(cc1)-[#6](=[#6]-1/[#6]-[#6]-[#7](-[#6]-[#6]-[#6]-[#7]2-c3cccc4cccc(c34)S2(=O)=O)-[#6]-[#6]-1)\c1ccc(F)cc1

InChI Key InChIKey=DMYVDWKBRXSJBY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50010031   

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
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Curated by ChEMBL
LigandPNGBDBM50010031(2-(3-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidi...)
Affinity DataIC50:  603nMAssay Description:The concentration required to inhibit [3H]spiperone binding to dopamine receptor D2 in rat brain membranes (in vitro)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
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Curated by ChEMBL
LigandPNGBDBM50010031(2-(3-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidi...)
Affinity DataIC50:  50nMAssay Description:The concentration required to inhibit [3H]prazosin binding to Alpha-1 adrenergic receptor in rat brain membranes was measured (in vitro)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
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Curated by ChEMBL
LigandPNGBDBM50010031(2-(3-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidi...)
Affinity DataIC50:  11nMAssay Description:The concentration required to inhibit [3H]ketanserin binding to 5-hydroxytryptamine 2 receptor in rat brain membranes (in vitro)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed