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BDBM50010441 CHEMBL4083309

SMILES: Fc1ccccc1C(=O)NCC1NCCc2ccccc12

InChI Key: InChIKey=OKKPPBSDWXKISO-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50010441   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mu-type opioid receptor


(Homo sapiens (Human))
BDBM50010441
PNG
(CHEMBL4083309)
Show SMILES Fc1ccccc1C(=O)NCC1NCCc2ccccc12
Show InChI InChI=1S/C30H32N2O8/c1-11(2)19-15-7-13(5)21(27(35)23(15)17(9-31-39)25(33)29(19)37)22-14(6)8-16-20(12(3)4)30(38)26(34)18(10-32-40)24(16)28(22)36/h7-8,11-12,33-38H,9-10H2,1-6H3
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PC sid
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Similars

Article
PubMed
n/an/an/an/a 3.28E+3n/an/an/an/a



National Health Research Institutes

Curated by ChEMBL


Assay Description
Agonist activity at human MOR expressed in CHO-K1 cells co-expressing Galpha 15 assessed as increase in intracellular calcium release incubated for 1...


Eur J Med Chem 126: 202-217 (2017)


Article DOI: 10.1016/j.ejmech.2016.09.003
BindingDB Entry DOI: 10.7270/Q2RB76TS
More data for this
Ligand-Target Pair