BDBM50010736 CHEMBL78083::N,N'-Bis-(4-ethyl-phenyl)-guanidine
SMILES CCc1ccc(NC(N)=Nc2ccc(CC)cc2)cc1
InChI Key InChIKey=DXGARAMIKHFTJV-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50010736
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience
Curated by ChEMBL
Cambridge Neuroscience
Curated by ChEMBL
Affinity DataIC50: 245nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge Neuroscience
Curated by ChEMBL
Cambridge Neuroscience
Curated by ChEMBL
Affinity DataIC50: 1.39E+3nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience
Curated by ChEMBL
Cambridge Neuroscience
Curated by ChEMBL
Affinity DataIC50: 245nMAssay Description:In vitro inhibitory activity against [3H]DTG binding to Sigma opioid receptor in guinea pig brain membrane homogenatesMore data for this Ligand-Target Pair