BDBM50010747 CHEMBL543201::CHEMBL78777::N,N'-Bis-(3-ethyl-phenyl)-guanidine
SMILES CCc1cccc(NC(N)=Nc2cccc(CC)c2)c1
InChI Key InChIKey=HCXWPWPGUTZRDL-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50010747
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience
Curated by ChEMBL
Cambridge Neuroscience
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience
Curated by ChEMBL
Cambridge Neuroscience
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:In vitro inhibitory activity against [3H]- (+)-3-PPP binding to Sigma opioid receptor in guinea pig brain membrane homogenatesMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience
Curated by ChEMBL
Cambridge Neuroscience
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience
Curated by ChEMBL
Cambridge Neuroscience
Curated by ChEMBL
Affinity DataIC50: 8.30nMAssay Description:In vitro inhibitory activity against [3H]DTG binding to Sigma opioid receptor in guinea pig brain membrane homogenatesMore data for this Ligand-Target Pair