BDBM50014050 CHEMBL43958::{1-[1-(1-Cyclohexylmethyl-4-formylamino-2,3-dihydroxy-butylcarbamoyl)-2-(3H-imidazol-4-yl)-ethylcarbamoyl]-2-phenyl-ethyl}-carbamic acid tert-butyl ester

SMILES CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)[C@@H](O)CNC=O

InChI Key InChIKey=SRXTZSLIJDIGDB-OBBCHVIHSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50014050   

TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014050(CHEMBL43958 | {1-[1-(1-Cyclohexylmethyl-4-formylam...)
Affinity DataIC50:  63nMAssay Description:In vitro inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014050(CHEMBL43958 | {1-[1-(1-Cyclohexylmethyl-4-formylam...)
Affinity DataIC50:  8nMAssay Description:In vitro inhibition of purified human renal renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed