BDBM50014816 6-{2-[2-Ethyl-4-(4-fluoro-phenyl)-6-phenyl-pyridin-3-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL350895

SMILES CCc1nc(cc(-c2ccc(F)cc2)c1CCC1C[C@@H](O)CC(=O)O1)-c1ccccc1

InChI Key InChIKey=PNHBRYIAJCYNDA-VQCQRNETSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50014816   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Hoechst

Curated by ChEMBL
LigandPNGBDBM50014816(6-{2-[2-Ethyl-4-(4-fluoro-phenyl)-6-phenyl-pyridin...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed