BDBM50014822 (E)-4-Hydroxy-6-{2-[2-isopropyl-4-(4-methoxy-phenyl)-6-phenyl-pyridin-3-yl]-vinyl}-tetrahydro-pyran-2-one::CHEMBL2368194
SMILES COc1ccc(cc1)-c1cc(nc(C(C)C)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1)-c1ccccc1
InChI Key InChIKey=RHFOAKIAPXDZKW-DOZDWOLESA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50014822
Affinity DataIC50: 150nMAssay Description:Inhibition of cellular HMG-CoA reductase in cultures of human HEP G2 cells, determined by decreased incorporation of sodium [14C]-acetate into choles...More data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Hoechst
Curated by ChEMBL
Hoechst
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:In vitro inhibition of rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair